This week CANDLab senior Jasmyne Pierre presented her thesis on "Protection and vulnerability in the face of trauma: discrimination, ethnic identity, and perceived stress" at her residential college's Mellon Forum. Congratulations to Jasmyne on a wonderful talk!
Dr. Gee awarded 2020 APS Janet Taylor Spence Award
Congrats to Dr. Dylan Gee on receiving the 2020 Janet Taylor Spence Award for Transformative Early Career Contributions from the Association for Psychological Science! Named for APS’s first elected President, the Spence Award recognizes early-career researchers who have made transformative contributions to the field of psychological science, such as establishing new paradigms within a subject area or advancing research that cuts across fields of study. Dr. Gee will be honored at the upcoming APS Convention in Chicago. Read more about this award here.
New study on safety signal learning from CANDLab and Weill Cornell collaborators
A cross-species collaborative study between the CANDLab and Dr. Francis Lee's lab at Weill Cornell Medicine was recently published in PNAS. In this new research we found that learned safety signals reduced threat responding across mice and humans. In mice (led by co-first author Dr. Heidi Meyer), fiber photometry recordings demonstrated that ventral hippocampal neurons projecting to prelimbic cortex (but not infralimbic cortex or the basolateral amygdala) were involved in conditioned inhibition via learned safety. Parallel findings in humans (led by co-first author Paola Odriozola) demonstrated the involvement of hippocampal-dorsal ACC (but not hippocampal-ventromedial PFC or hippocampal-amygdala). Importantly, this pathway differed from the ventromedial PFC-amygdala pathway implicated in fear extinction. These findings have broad implications for optimizing interventions for anxiety disorders and for investigating novel approaches to fear reduction. Read more about these findings here.
New CANDLab study on PTSD in youth
The CANDLab has published a new study on brain development in youth with post-traumatic stress disorder (PTSD). This research was led by MD/PhD student Sahana Kribakaran and conducted in collaboration with Drs. Andrea Danese, Konstantinos Bromis, and Matthew Kempton. You can find the study here and a summary below:
In this work we aimed to address the following questions: What differences in brain volume are associated with pediatric PTSD? Do findings in pediatric PTSD differ from those in adults with PTSD? To what extent do these differences relate to PTSD vs trauma exposure itself? To what extent are these differences specific to PTSD vs anxiety and depression, which are often co-occurring in youth with PTSD?
Findings from individual studies of youth with PTSD have been varied, and some have suggested that there are no differences in hippocampal or amygdala volumes between youth w/ and w/o PTSD. In this meta-analysis we found that pediatric PTSD was associated with smaller gray matter volume in various regions including the hippocampus. This hippocampal alteration was similar to that observed in adults with PTSD. Age was a moderator for hippocampal volume, with studies of older individuals more likely to observe smaller volume in pediatric PTSD. Sex was a moderator for hippocampal and amygdala volume, with studies with higher percentages of females more likely to observe smaller volume in pediatric PTSD.
Youth with PTSD differed from youth who were exposed to trauma but did not develop PTSD. Whereas pediatric PTSD was associated with smaller hippocampal and amygdala volumes, trauma exposure without PTSD was associated with larger volumes. Thus, volumetric differences in pediatric PTSD are unlikely to be explained solely by trauma exposure. Findings suggested that the volumetric differences observed in pediatric PTSD may be distinct from pediatric depression and partially overlapping with pediatric anxiety.
Future research will benefit from examining co-occurring clinical presentations that are common among youth exposed to trauma, dimensional approaches that may better capture heterogeneous symptoms, and study designs that can clarify developmental effects of trauma and PTSD. In the discussion we highlight important details on interpretations and implications of this study. Much work remains to be done, and we hope this study helps to provide insight into the nature of brain development among youth with PTSD!
Summer interns from Yale Summer Science Institute present final projects!
Congratulations to our high school summer interns from the Yale Summer Science Institute on presenting your final projects! Thank you Lesly Mellado, Manny Candelo-Diaz, and Achintya Bairat for your work in CANDLab this summer!
Nisha Sridhar presents at the CSC summer poster session!
Congrats to Nisha Sridhar, CANDLab summer intern, who delivered a stellar presentation at the Yale Child Study Center summer poster session! Nisha's summer project focused on the effects of early adversity on fear learning.
Jasmyne Pierre awarded undergraduate research grant!
CANDLab undergraduate Jasmyne Pierre was recently awarded the Mamie Phipps Clark Diversity Undergraduate Research Grant from Psi Chi! This award will fund Jasmyne's senior thesis on discrimination-related stress and mental health. Congratulations to Jasmyne on this very well deserved award!
Welcome, CANDLab summer RAs!
Welcome to our CANDLab summer research assistants! We're looking forward to a summer of exciting science together!
Congratulations, CANDLab Seniors!
Congratulations to all of our amazing graduating research assistants! Thank you for your important contributions to our work on the developing brain. We are so lucky to have had you in lab, and you will all be so missed! We can’t wait to hear of all of your future accomplishments!
CANDLab Seniors Present Theses
CANDLab senior undergraduate research assistants, Adrian Lin, Amy Kwarteng, Cristian Hernandez, Emma Goodman, Janeen Thomas and Rob Colgate, presented blitz talks about their theses at our last lab meeting of the semester. It was amazing getting to hear about their hard work on a wide range of important topics relating to the development of the child and adolescent brain. Congratulations on your incredible senior projects and theses!
Dr. Gee receives Yale research prize
Congratulations to Dr. Gee, who was awarded the Arthur Greer Memorial Prize for Outstanding Research!
Dr. Gee receives Jacobs Foundation Early Career Research Fellowship
Dr. Gee was recently awarded the Jacobs Foundation Early Career Research Fellowship. This unique global program supports cutting-edge research on youth development. The three-year grant will support exciting new work in the lab on the role of caregivers and early experiences in shaping emotional learning and regulation during childhood and adolescence! You can read more about the program and Dr. Gee's work here.
Dr. Gee awarded Yale teaching prize
Congratulations to Dr. Gee who was awarded the Poorvu Family Fund for Academic Innovation award! Read more about this honor here.
Emily Cohodes named Nathan Hale Fellow
Ph.D. student Emily Cohodes was recently named a Nathan Hale Associates fellow by Yale’s Graduate School of Arts and Sciences. Congratulations, Em!
CANDLab research featured in NIMH Director's update
The CANDLab is excited to be launching a new clinical trial of a novel treatment for pediatric anxiety disorders! We will be studying how the brain changes during treatment in ways that help to reduce children's anxiety. The study was recently featured in a newsletter from the NIMH Director, and you can read more here!
Congrats to Emily Cohodes on ISDP travel award!
PhD student Emily Cohodes was recently awarded a travel award to attend and present her research at the 51st annual meeting of the International Society for Developmental Psychobiology, which will take place in San Diego this fall. Congrats to Em! You can read more about the upcoming meeting here: http://isdp.org/current/
CANDLab now accepting applications for full-time research assistant!
The Clinical Affective Neuroscience & Development Lab at Yale, directed by Dr. Dylan Gee, is seeking a full-time research assistant to begin in summer or fall 2018 (start date flexible) to coordinate a new NIMH-funded study of the neural mechanisms underlying a novel psychosocial treatment for pediatric anxiety disorders. The lab uses behavioral, psychophysiological, and neuroimaging techniques to study the development of anxiety and stress-related disorders across childhood and adolescence and ways to optimize interventions based on the developing brain.
Primary responsibilities will include recruiting and screening participants; acquiring, managing, and analyzing data (behavioral, psychophysiological, MRI); working with children, adolescents, and their parents in a research setting; performing administrative duties (e.g., assisting with IRB protocols and grants); and coordinating the lab’s collaboration with the Yale Child Study Center (co-PI: Dr. Eli Lebowitz).
Requirements include a Bachelor’s degree in psychology, neuroscience, or related field; interest in clinical psychology and neuroscience; and excellent organizational, interpersonal, communication, and time management skills. Competitive candidates will have prior research experience with children and adolescents and/or neuroimaging experience. A 2-year commitment is preferred.
This position is ideal for those interested in pursuing a Ph.D. in clinical or developmental psychology or neuroscience. The laboratory is located within the Department of Psychology and collaborates closely with the Yale Child Study Center, thus providing an excellent training environment at the intersection of research and clinical practice. The research assistant will participate in all aspects of the research process, have opportunities to work on a variety of exciting research projects, and gain experience working with both typically developing and clinical populations. The ideal candidate will likely make intellectual contributions to the lab’s research, which may result in opportunities to co-author manuscripts, and will benefit from the vibrant scientific community at Yale.
Applicants should send a cover letter (describing research experiences, interests, and long-term goals), CV, and contact information for 2-3 references to Dylan Gee at firstname.lastname@example.org.
Congrats, CANDLab Seniors!
Congratulations to CANDLab seniors Aviva Abusch, Elizabeth Kitt, Sarah McCauley, Hopewell Rogers, and Mackenzye Smith on their excellent senior projects, theses, and graduations from Yale! We are going to miss you so much!
Camila Caballero awarded Ford Fellowship!
The CANDLab congratulates Ph.D. student Camila Caballero on her recent Ford Foundation Fellowship! Through its Fellowship Programs, the Ford Foundation seeks to increase the diversity of the nation’s college and university faculties by increasing their ethnic and racial diversity, to maximize the educational benefits of diversity, and to increase the number of professors who can and will use diversity as a resource for enriching the education of all students. This national competition is administered by the National Academies of Sciences, Engineering, and Medicine on behalf of the Ford Foundation. Read more here: http://sites.nationalacademies.org/PGA/FordFellowships/index.htm. Way to go, Camila!
Congrats to Camila Caballero on Bourne Fellowship!
We're excited to share that CANDLab Ph.D. student Camila Caballero was recently selected as a Jonathan Bourne Fellow at Yale. Congratulations, Camila!
Congrats to Emily Cohodes on APA Early Graduate Student Researcher Award!
Congrats to CANDLab Ph.D. student Emily Cohodes, who has received the APA's Early Graduate Student Researcher Award! This award recognizes students for conducting outstanding research early in their graduate training.
Luise Pruessner receives DAAD travel award!
Luise Pruessner, a visiting Fulbright scholar in the CANDLab and current Ph.D. student at the University of Heidelberg, received a travel award from the Deutscher Akademischer Austauschdienst to present her research on fear learning and intolerance of uncertainty at the 51st annual meeting of the Association for Behavioral and Cognitive Therapies (ABCT) in San Diego. Congrats to Luise!
CANDLab accepting full-time RA applications
The CANDLab is seeking a full-time research assistant to begin in early or mid 2018 (start date flexible). The lab uses behavioral, psychophysiological, and neuroimaging techniques to study the development of anxiety disorders across childhood and adolescence. We are especially interested in typical and atypical trajectories of brain development related to emotional behavior, the effects of early-life adversity, and translating knowledge from basic science to optimize clinical treatments for anxiety and stress-related disorders. The laboratory is located within the Department of Psychology, which provides an excellent research and training environment.
Primary responsibilities will include screening and recruiting participants; acquiring data (behavioral, psychophysiological, MRI); managing and analyzing data; working with children, adolescents, and their parents in a research setting; assisting in experimental paradigm development; and managing the lab and performing administrative duties (e.g., assisting with IRB protocols and grants).
Requirements include a Bachelor’s degree in psychology, neuroscience, or related field; interest in clinical developmental neuroscience; strong statistical and technical skills (e.g., R, MATLAB, Python); and excellent organizational, interpersonal, communication, and time management skills. Competitive candidates will have prior research experience with children and adolescents, neuroimaging experience (e.g., fMRI data analysis in FSL, AFNI, or a similar platform), and familiarity with IRB protocol submissions. A 2-year commitment is required.
This position is ideal for those interested in pursuing a Ph.D. in clinical or developmental psychology or neuroscience. The research assistant will participate in all aspects of the research process, have opportunities to work on a variety of exciting research projects, and gain experience working with both typically developing and clinical populations. The ideal candidate will likely make intellectual contributions to the lab’s research, which may result in opportunities to co-author manuscripts, and will benefit from the vibrant scientific community at Yale.
Applicants should send a cover letter (describing research experiences, interests, and long-term goals), CV, and contact information for 2-3 references to Dylan Gee at email@example.com.
CANDLab accepting postdoc applications
The CANDLab is currently accepting applications for a postdoctoral fellow to begin in summer or fall 2018 (flexible start date). The lab uses behavioral, psychophysiological, and neuroimaging techniques to study the development of anxiety disorders across childhood and adolescence. We are especially interested in typical and atypical trajectories of brain development related to emotional behavior, the effects of early-life adversity, and translating knowledge from basic science to optimize clinical treatments for anxiety and stress-related disorders. The laboratory is located within the Department of Psychology, which provides an excellent research and training environment.
The postdoctoral fellow will have the opportunity to contribute to ongoing NIH-funded research on pediatric anxiety and to develop independent studies within the broader aims of the lab. Requirements include a Ph.D. in psychology, neuroscience, or a related field. Applicants should have a strong publication record, experience with human neuroimaging, strong statistical training, and technical experience with fMRI analysis (e.g., FSL, AFNI, SPM) and programming. The ideal candidate will have excellent interpersonal and communication skills, the ability to work independently, and experience conducting research with developmental and/or clinical populations.
Applicants should send a cover letter describing relevant experience and interests, CV, and contact information for three references to Dylan Gee at firstname.lastname@example.org.
Emily and Paola selected to attend longitudinal imaging workshop
Ph.D. students Emily Cohodes and Paola Odriozola have been selected to attend the "Modeling Developmental Change: Practical Integration of Advanced Neuroimaging and Statistical Methods" pre-meeting workshop at the Flux Congress in Portland, OR, and Paola received a travel award. Longitudinal MRI datasets require special consideration for processing and analysis, yet the field as a whole has not standardized best practices for these datasets, which could be one reason why it is difficult to replicate results across laboratories and research studies. This two-day workshop will teach best practices for processing, analyzing, modeling, and interpreting longitudinal neuroimaging data. This will help researchers conduct robust and reproducible research on how the brain and cognition change across development. We're excited to apply these methods to our ongoing longitudinal studies in the CANDLab! Congrats, Paola and Em!
Welcome to Camila Caballero!
Welcome to Camila Caballero, who joins the CANDLab as a first-year graduate student in Yale's clinical psychology program!
Dr. Gee attends WEF Annual Meeting of the New Champions
Dr. Gee recently participated in the World Economic Forum's Annual Meeting of the New Champions in Dalian, China. She was selected as part of the Young Scientists community, which "brings together the most forward-thinking and advanced young scientific minds in the world. They are selected from all regions and a wide range of disciplines, and have a track record of advancing the frontiers of science, technology and environment in areas of high societal impact. In their work, they exhibit exceptional creativity, thought leadership and high growth potential. Under the age of 40, these individuals have demonstrated their commitment to public service and actively play a transformational role in integrating scientific knowledge into society for the public good." Dr. Gee discussed her research and the role of neuroscience in the Fourth Industrial Revolution alongside 2,000 business leaders, policymakers, and fellow scientists. You can read more about the scientists selected for the 2017 cohort here.
Emily Cohodes awarded NSF GRFP!
Congratulations to Emily Cohodes, who has received the NSF Graduate Research Fellowship Program award! Read more about the GRFP here.
Luise Pruessner receives SPR travel award!
Congrats to Luise Pruessner, who received a travel award to attend the Society for Psychotherapy Research annual meeting! The meeting will be held in Toronto in June.
Emily Cohodes selected for Multimodal Neuroimaging Training Program!
Congrats to CANDLab Ph.D. student Emily Cohodes, who received a travel award to attend the Multimodal Neuroimaging Training Program hosted by Pitt and Carnegie Mellon! The symposium will take place in May, and this year's topic is "Advances in Health Neuroscience and Multimodal Neuroimaging." Learn more about the training here.
Dr. Gee selected as APS Rising Star!
Dr. Gee has been selected as a Rising Star by the Association for Psychological Science. The Rising Star designation recognizes outstanding psychological scientists in the earliest stages of their research career post-PhD whose innovative work has already advanced the field and signals great potential for their continued contributions. More information on the Rising Star award is available here.
Paola selected for SRCD Millenium Scholars Program!
Congrats to CANDLab Ph.D. student Paola Odriozola, who was selected for the SRCD Millenium Scholars Program! The program will take place at the 2017 annual meeting in Austin, TX, in April. The Frances Degen Horowitz Millennium Scholars Program was developed as a vehicle to encourage and support scholars from under-represented ethnic/racial groups from North America in pursuing graduate work in developmental science. To that end, the program provides educational and professional development for these scholars, giving them a launching point for a career in the field of child development. Read more about the program here.
Paola Odriozola to attend UCLA Tools of the Trade Workshop
Congratulations to Paola, who received a travel fellowship for the upcoming Tools of the Trade Workshop at UCLA! The workshop will focus on best practices in human neuroimaging methods and is funded by the NIH and Stanford Center for Reproducible Neuroscience. Read more about the workshop here.
Dr. Gee's research featured on the NIH Director's Blog
Dr. Gee and her research were recently profiled on the NIH Director's Blog by Dr. Francis Collins. Read more here: https://directorsblog.nih.gov/2016/07/21/creative-minds-helping-more-kid...
Dr. Gee featured on The Academic Minute
Dr. Gee was recently interviewed on The Academic Minute to discuss the increased risk for anxiety in adolescence. Hear more on the research at http://academicminute.org/2016/07/dylan-gee-weill-medical-college-at-cor...
Paola Odriozola awarded NSF fellowship!
Ph.D. student Paola Odriozola has been awarded an NSF Graduate Research Fellowship! Congrats, Paola!
Welcome to Emily Cohodes!
The CANDLab welcomes incoming Ph.D. student Emily Cohodes! Emily is joining Yale's psychology program.
Welcome to Paola Odriozola!
The CANDLab welcomes incoming Ph.D. student Paola Odriozola! Paola is joining Yale's neuroscience program.
Dr. Gee named one of "fifty scientists under 40" by World Economic Forum
Dr. Gee was recently selected as one of the top "fifty scientists around the world under 40" by the World Economic Forum. The Young Scientist community will engage with business and political leaders at the Forum’s Annual Meeting of the New Champions to contribute their scientific perspective and highlight the most up-to-date trends. Young Scientists are selected for their contributions to advance the frontiers of science, engineering or technology in areas of high societal impact.
PNAS paper featured on PBS News Hour
Our new paper in PNAS on adolescent risk for anxiety, which was conducted in the labs of BJ Casey and Francis Lee and in collaboration with the PING Consortium, has been featured in news outlets including PBS News Hour (http://www.pbs.org/newshour/rundown/is-this-mutation-causing-your-teenag...) and the Huffington Post (http://www.huffingtonpost.com/entry/even-more-evidence-anxiety-can-be-bi...?).
Welcome to Luise Pruessner!
Welcome to Luise Pruessner, who is a Fulbright scholar from Heidelberg University who will be visiting the CANDLab during the 2016-2017 year!
Dr. Gee attends the NIH’s High Risk High Reward symposium
Dr. Gee recently attended the NIH’s High Risk High Reward symposium in Bethesda, MD, to present her latest research and receive the NIH Director's Early Independence Award, which will provide funding of up to $1.25M for a 5-year study of novel mechanisms of fear reduction in pediatric anxiety disorders.
Dr. Gee awarded the NIH Director’s Early Independence Award!
Dr. Gee has received the NIH Director’s Early Independence Award! Read more here: https://commonfund.nih.gov/earlyindependence/index
Dr. Gee receives NARSAD Young Investigator Award!
Dr. Gee has received a NARSAD Young Investigator Grant! Read more here: https://bbrfoundation.org/sites/bbrf.civicactions.net/files/file-downloa...
CANDLab accepting PhD applications
The CANDLab is currently accepting applications for doctoral students to begin in the Fall of 2016 at Yale! Apply here: http://psychology.yale.edu/graduate/admissions/applying-admission